Loratadine tablets should not be taken after the expiration date. Because the main ingredient of loratadine is antihistamine, if the expiration date is exceeded, the antihistamine effect of this drug will be greatly reduced, or in some cases, it will not have any antihistamine effect at all. Therefore, it is not able to treat allergic diseases such as hives or eczema. It is important to throw away the expired loratadine and buy new anti-allergy drugs that have just been produced or are within the expiration date, or you can use loratadine or other antihistamines, such as epalrestine or levocetirizine hydrochloride for anti-allergy treatment.