Whether syphilis can be completely cured is related to the severity of the disease and whether it is treated regularly. Syphilis is a sexually transmitted disease caused by syphilis spirochete infection, which can invade the organs of the whole body and cause multi-organ damage. Early syphilis symptoms are mild and usually only accumulate in the skin and mucous membranes. With the aggravation of the disease, it will also affect the cardiovascular system and the nervous system, appearing neurosyphilis, cardiovascular syphilis and so on, seriously affecting the health of the body. Generally in the early stage of syphilis, after active standardized treatment and follow-up, it can be cured. If the condition is more serious, and complicated by cardiovascular, neurological and other systems of damage, this situation although syphilis can be better controlled, but syphilis brought about by the various systems of damage is irreversible. Therefore, the discovery of syphilis should be timely medical treatment. Generally speaking the earlier the treatment, the better the prognosis.