To determine whether hepatic calcified foci are caused by a tumor, the diagnosis can be made by taking into account the patient’s past medical history as well as relevant findings such as pathology and tumor markers. 1. Past medical history. It should be clarified whether the patient has a history of liver abscess, alcoholic liver disease, hepatitis B and other liver diseases, because the foci associated with these diseases are likely to form the present calcified foci after maturation and mechanization. 2. Serum tumor markers. Such as alpha-fetoprotein, CA199, CA125, etc. The results of nuclear magnetic resonance (MRI) and enhanced CT can effectively assist in the diagnosis. 3. Other examination results. If the diagnosis is difficult, it is feasible to carry out liver puncture examination and take pathological biopsy to clarify the nature of the lesion, and the pathological result is the gold standard. After checking out the liver calcification foci, we should consult a doctor in time, and perform relevant examinations to clarify the cause of the disease, and then carry out further diagnosis and treatment.