There is no such thing as what is the best filler for sunken eye sockets. Each patient has different needs and personal constitution, so the suitable filler material is different for each person, and it is impossible to conclude what is the best filler. If you want to fill the natural effect, you can follow the doctor’s advice to fill with autologous fat or artificial soft tissue filler for injection filling. Artificial soft tissue fillers are divided into various types, such as collagen, hyaluronic acid, etc. Generally, after injecting artificial soft tissue fillers, they will be gradually metabolized in half a year to one year. Autologous fat metabolism can be permanent. Generally, injection of artificial soft tissue fillers is not recommended for women who are breastfeeding or pregnant. Autologous fat fillers are not recommended for patients with heart failure, hypertensive heart disease, or other medical conditions. Some patients may experience adverse reactions such as skin itching and fever after filling. Patients are advised to consult their doctors for a more suitable filler according to their own situation.