Splenomegaly with normal liver function may be caused by infectious factors, bruising, blood disease, connective tissue disease, spleen disease and so on. 1. Infectious factors: most commonly seen in viral infection, bacterial infection, spirochete infection, parasitic infection can cause splenomegaly, but liver function is normal. 2. Siltation: for example, chronic constrictive pericarditis, large amount of pericardial effusion and so on cause splenomegaly, but liver function is normal. 3. Hematological diseases: mostly seen in acute and chronic leukemia, hemolytic anemia, multiple myeloma, malignant lymphoma, hypersplenism and so on. 4. Splenic diseases: splenic tumor, splenic cyst, splenic malignant tumor, splenomegaly and normal liver function can occur. If the liver function is normal with splenomegaly, it is recommended to consult a doctor in time to clarify the cause of the disease and treat it as early as possible.