Running ankle pain, if it is caused by excessive force on the ankle area, or caused by cartilage or ligament damage, etc., you can improve the symptoms through general treatment, and physical therapy or medication can be used to treat the pain accompanied by swelling. 1. General treatment: running ankle pain, need to pay attention to rest, relax the ankle. If necessary, can be fixed plaster braking, avoid strenuous exercise, elevate the affected limb, conducive to venous blood return, reduce swelling, relieve pain. 2. Physiotherapy: Running ankle pain, within 72 hours, can be the first cold compresses, and then hot compresses after 72 hours, to relieve the ankle swelling, pain. You can also take local massage, infrared physiotherapy, low and medium frequency electrotherapy and other physical methods to relieve the symptoms. 3. Oral medication: Non-steroidal drugs such as ibuprofen, celecoxib and indomethacin can be taken orally to improve the symptoms. If the pain in the ankle area is obvious, you can also apply topical ointment, such as diclofenac diethylamide cream. All of the above medications should be used under the guidance of a doctor, avoid self-medication. It is recommended to consult a doctor in time and follow the doctor’s instructions.