Sore throat when swallowing is clinically associated with the following diseases. The first one is most commonly seen as acute pharyngitis and acute tonsillitis. Such patients can be seen to have obvious pharyngeal congestion, bilateral tonsillar congestion, and even the possibility of suppuration during clinical examination. Clinical anti-inflammatory treatment, plus nebulization treatment, etc., is usually almost sufficient. The second type is that the patient may have dyspnea, gasping for air, etc. in addition to pain when swallowing, and the location of the pain is close to the laryngeal node, below the throat. In this case, the possibility of acute epiglottitis cannot be ruled out, and symptomatic treatment with adequate antibiotics plus adequate hormones is needed to avoid life-threatening conditions such as asphyxia. The third kind of individual patients, if they have cancer, such as advanced hypopharyngeal cancer, swallowing pain will also occur if the main body of cancer has broken down and eroded, in this case, treatment with medication has no effect.