Drinking red and itchy palms, usually have the following factors. 1, such as some special physique, prone to alcohol allergy or alcoholism, there will be red palms and especially itchy skin allergy symptoms. Especially in many kinds of alcohol drinking together, such as drinking beer and then drinking red wine, white wine, there will be a kind of cross alcohol allergic reaction clinical symptoms, first of all, will lead to red palms, followed by itching of the skin. 2, for example, drinking alcohol drinking spoiled or expired fake wine, such as methanol poisoning will also appear such clinical manifestations. 3, drinking too much alcohol will appear in the alcohol in the liver under the action of the enzyme of alcohol dehydrogenase converted to acetaldehyde, which will be used as a substitute for alcohol in the liver. Under the action of ethanol dehydrogenase in the liver, ethanol is converted into acetaldehyde, which has the effect of expanding capillaries, especially in the upper limbs and hands, where capillaries are more developed. Therefore, it will lead to the clinical manifestation of itchy and red palms after drinking.