Children with fever and diarrhea with blood in the stool are often seen in infectious diarrhea disease, the treatment needs to strengthen the daily care, symptomatic treatment (such as oral montelukast to stop diarrhea) and causative treatment (such as cefixime anti-infective). 1. Enhance daily care: these children are recommended to eat normally, do not advocate fasting, eat the usual diet can be, such as vomiting symptoms, it is necessary to adjust the diet, such as eating easy to digest food, such as vomiting frequently, it is necessary to fast for a short period of time. 2. Symptomatic treatment: if fever occurs during the course of the disease, it is necessary to reasonably reduce fever, if the temperature exceeds 38.5℃, it is necessary to use ibuprofen or acetaminophen to reduce fever, and at the same time, oral Clostridium Typhimurium and montelukast to alleviate the symptoms of diarrhea and blood in stools, and if dehydration occurs during the course of the disease, it is necessary to supplement the oral rehydration salts and other treatments. 3. Anti-causal treatment: If the above phenomenon is caused by bacterial infection (e.g. invasive Escherichia coli), antibacterial drugs, such as cefaclor, cefixime, etc., are usually needed for anti-infective treatment. In viral infections, no specific treatment is necessary. All of the above drugs should be used under the supervision of a physician, and it is recommended to actively consult a specialist for treatment.