Insulin dose is related to glycated hemoglobin, body weight, etc. The general starting dose is 0.1-0.2 U/kg/d, but the dose is different for different patients, and it needs to be administered under the guidance of a doctor, not applied by oneself. Patients with type 2 diabetes mellitus in oral hypoglycemic drug therapy combined with intermediate-acting insulin or long-acting insulin injection at bedtime. The starting dose of insulin is 0.1-0.2 U/kg/d, if glycated hemoglobin >8%, 0.2-0.3 U/kg/d; for body mass index greater than 25 kg/m2, the insulin dose is 0.3 U/kg/d. Patients need to adjust the insulin dosage according to the fasting blood glucose and 2-hour postprandial blood glucose levels, usually every 3 to 5 d, depending on the blood glucose level each time to adjust 1-4 U until the blood glucose standard. Insulin dosage calculation formulas are different according to different indicators, and patients are advised to consult their medical professionals.