Itchy perineum firstly can use Chuan Bai stop itching lotion or red nucleus gynecological cleansing lotion for local perineum cleaning, these two medicines can achieve the purpose of stopping itching. In addition, we should do laboratory tests to check whether the cause of itching is caused by vaginitis. If the routine test of leukorrhea proves that the patient has vaginitis, different antibacterial drugs will be applied according to the pathogens detected. If the infection is bacterial vaginitis or trichomonas vaginitis, it should be treated with metronidazole. If it is mycotic vaginitis, it should be treated with clotrimazole, an antifungal drug. If there is no problem with the leukorrhea, and the perineum is itchy, the first thing to consider is whether it is pruritus perineum, for pruritus perineum can be used estrogen ointment local application, in addition to some anti-itch lotion to carry out symptomatic treatment.