The causes of numbness of the big toe include physiological factors, peripheral neuropathy and lumbar spine diseases. 1. Physiological factors: due to incorrect posture and other reasons, the big toe is compressed for a short period of time and may have numbness symptoms, etc., after the compression is lifted, most of them can return to normal. 2. Peripheral neuropathy: This product is mainly due to diabetes, drug poisoning and other reasons leading to peripheral nerve damage, the onset of numbness of the big toe symptoms. In severe cases, there can be sock-like sensory impairment. 3. Lumbar spine diseases: including lumbar spinal stenosis, lumbar disc herniation, sacroiliac arthropathy and other compression of the sciatic nerve in the lumbar region, it is possible to make the toes have sensory disorders, and the patient will consciously have numbness of the big toe. There are many causes of numbness in the big toe, so we suggest that patients should consult the doctor in time to clarify the cause and have reasonable treatment under the doctor’s guidance.