There is no specific relationship between the ki67 value and the diagnosis of colon cancer, and the diagnosis of colon cancer is mainly through histopathological biopsy. ki67 is one of the indicators in immunohistochemistry of tumor pathology, which belongs to proliferation index. The level of this indicator can indicate the activity of tumor cell division and proliferation, and the higher the indicator is, the more active the proliferation and division of tumor cells are, which can reflect the malignant degree of the tumor to a certain extent. The diagnosis of colon cancer needs to be confirmed by histopathological biopsy, including ki67, which can evaluate the necessity of chemotherapy to a certain extent. However, the level of ki67 is not specific to the diagnosis of colon cancer, and ki67 can be elevated in other tumors such as breast cancer. When abnormal ki67 indexes are found, it is recommended to consult a doctor in time to clarify the cause of its elevation, so as to avoid serious consequences.