Postoperative anastomotic edema of esophageal cancer is generally a normal physiological phenomenon, or it may be caused by postoperative infection, patients can take medication and general treatment. When patients with esophageal cancer have anastomotic edema after surgery, it may be due to the congestion of local tissues caused by surgery, and patients will have poor blood return, thus anastomotic edema occurs, which is a normal physiological phenomenon. Patients can take oral hydrochlorothiazide tablets, torasemide tablets and other diuretic drugs as prescribed by doctor, which can help patients to eliminate edema. Postoperative anastomotic edema of esophageal cancer patients may also be caused by postoperative infection, which is caused by improper postoperative care, resulting in anastomotic infection, and patients will have symptoms such as anastomotic edema, pain and so on. It is recommended that patients take oral antibiotic treatment such as amoxicillin capsule and erythromycin capsule as prescribed by doctor, which can eliminate inflammation and relieve edema. Patients with esophageal cancer who have the symptom of anastomotic edema after operation should inform the doctor in time and take medication as prescribed by doctor, and should not take medication by themselves.