Alkaline phosphatase, glutamyl transpeptidase, bilirubin are elevated consider the presence of gallstones, cirrhosis, alcoholic liver disease and other diseases caused by the need for targeted treatment under the guidance of a doctor, such as general treatment, drug therapy. 1. Gallstones: fasting is required in the acute stage, diclofenac can be used for pain relief in severe pain, metronidazole, amoxicillin and other medications can be used when accompanied by bacterial infections, and surgery needs to be considered in the case of recurring biliary colic, a large number of stones, and the diameter of the stones is long. 2. Cirrhosis: Reduced glutathione and adenosylmethionine can be used for hepatoprotective treatment, and patients with ascites need to limit the intake of water and sodium, as well as the use of furosemide, spironolactone and other medications. 3. Alcoholic liver disease: need to quit drinking, maintain a low-fat diet, appropriate physical exercise, can also use silymarin and other liver-protecting drugs. If alkaline phosphatase, glutamyl transpeptidase and bilirubin are elevated, it is recommended to go to the hospital and receive standardized treatment under the guidance of the doctor.