With the development of research on coronary heart disease, it is believed that it is the stagnation of qi and blood flow, the internal growth of stagnant blood, stasis of blood vessels, and the development of chest paralysis and heart pain, and it is recognized that the main pathogenesis of coronary heart disease is the stasis of heart blood. Modern medical research confirms that hyperlipidemia and atherosclerosis are directly related to the development of coronary heart disease, and many clinical manifestations of atherosclerosis and hyperlipidemia are consistent with blood stasis in Chinese medicine. Many clinical manifestations of atherosclerosis and hyperlipidemia are consistent with the blood stasis evidence in TCM. Clinical treatment of coronary heart disease according to the blood stasis evidence is more satisfactory with the method of activating blood and removing blood stasis. Especially in improving myocardial blood supply, dilating coronary arteries, reducing vascular resistance, lowering lipids, adjusting fibrinolytic activity, and protecting endothelial cells, all have effects. It is confirmed that coronary heart disease and blood stasis evidence are closely related, and the important treatment for coronary heart disease is to activate blood circulation and remove blood stasis. Angelica sinensis, Chuanxiong rhizome, Pueraria lobata, Momordica charantia, Safflower, Trigonella, Panax quinquefolium, Blood exhaustion, Red peony, White peony, etc. are commonly used in clinical practice, and the treatment is based on the evidence and added or subtracted according to the condition.