Breast nodules are common breast diseases in women and can be divided into three categories according to etiology: first, benign nodules such as cystic hyperplasia of the breast, which is common in women of childbearing age, with clinical manifestations of periodic breast swelling and pain accompanied by hyperplastic nodule formation, the size of the nodule increases before menstruation and can shrink after menstruation, which can be cured by local heat physiotherapy and oral prolotherapy or Xiaojinwan symptomatic treatment. If the nodules are progressively increasing when the drug treatment is not effective, you should be alert to the possibility of malignant change and timely surgical excision treatment. Secondly, benign and malignant junction nodules such as fibroids and intraductal papillomas, which have no obvious clinical manifestations, are often found during breast palpation and have malignant potential, and should be actively treated surgically once diagnosed. Thirdly, malignant nodules such as breast cancer often have no characteristic clinical manifestations in early stage, but when the disease progresses to advanced stage, orange peel sign or dimple sign may appear.