When coughing after deep breathing occurs, it is likely to be caused by a respiratory infection or by a high airway reaction. Either way, there is a relative narrowing of the airway, which occurs when the air flow is high during deep breathing, and the air irritates the airway, causing the cough to occur. First of all, the cause of the cough should be identified, and the effect of targeted treatment is better. In case of airway hyperresponsiveness, drugs that relax the smooth muscles of the airways, such as chewing a chewable tablet of montelukast sodium before going to bed, as well as long-term nebulized inhalation of glucocorticoids and bronchodilators, such as nebulized inhalation of terbutaline sulfate and budesonide, should be used for treatment. In case of respiratory infections, appropriate antibiotics or antiviral drugs should be selected for treatment according to the type of infection. In addition, cough suppressants such as Ambroxol Hydrochloride or Ambrotero Oral Solution are also needed.