Patients should not drink alcohol for 12 hours after taking Crypto, the drug is not completely metabolized from the body, and drinking alcohol at this time may lead to adverse reactions. The main active ingredients include acetaminophen, amantadine hydrochloride, chlorpheniramine maleate, artificial oxymorphone and caffeine. Acetaminophen can play an antipyretic and analgesic role, patients should not drink alcohol during the use of acetaminophen. Drinking alcohol may aggravate the gastrointestinal reaction to the drug and may also affect liver function because acetaminophen may damage the liver, as may alcohol. In addition, both chlorpheniramine maleate and caffeine contained in crack may affect the central nervous system. Caffeine has a stimulant effect on the central nervous system; chlorpheniramine maleate has a sedative effect. Alcohol also affects the central nervous system and may have a sedative or euphoric effect, so drinking alcohol while using crack may aggravate the central nervous system side effects.