Antibiotics for acute sinusitis are usually used for about 1 to 2 weeks, depending on the condition. The recommended antibiotics for acute sinusitis are amoxicillin clavulanate potassium and second-generation cephalosporins, e.g., amoxicillin clavulanate potassium, cefuroxime and other medications are used for treatment under a doctor’s supervision. When some pathogenic bacteria are not sensitive, the effect is not obvious, and secretion culture plus drug sensitivity test is needed to guide the adjustment and use of antibiotics. At the same time with nasal spray glucocorticoid therapy, such as: budesonide nasal spray, fluticasone propionate nasal spray, etc.. Can also use mucus drainage agent, such as eucalyptus pinocchio enteric soft capsule, used to promote the nasal cavity, sinus mucopurulent nasal discharge to the outside. Acute sinusitis patients, should follow the doctor’s instructions to standardize the use of drugs and treatment.