The common causes of pain in the round bone below the patient’s big toe are mainly the following: First, when the patient is in strenuous activity, inadvertently causing local ligament strains, which can cause significant local pain, swelling and restricted activity. At this time, patients need to rest, adequate braking, topical application of blood-stasis cream, oral swelling and pain capsules, which can improve local blood circulation, promote faster recovery of the injured bone below the big toe and reduce local pain symptoms. Second, if the patient’s round bone below the big toe is injured more heavily, accompanied by local fractures, will also cause significant pain, the patient can improve the local X-ray or CT examination, to clarify the specifics of the fracture, as soon as possible to perform surgery for internal fixation. Post-operative treatment of anti-infection, analgesia and edema can effectively relieve local pain symptoms and promote early recovery of the patient’s injury.