Possible causes of hypertrophic cardiomyopathy: 1, generally and genetic relationship, can be caused by multiple single-gene mutations, so far has been found to have 7 genes, more than 70 kinds of mutations related to the disease, the most characteristic is located on chromosome 14 myosin heavy chain gene mutation caused by the different gene mutations lead to hypertrophic cardiomyopathy clinical manifestations and prognosis is also different; 2, catecholamines in the fetal period production or enhanced activity can lead to cardiomyocyte arrangement disorder and septal asymmetric hypertrophy; 3, low calcium ion concentration, myofilament tension increases, myofilament contractility enhancement, can induce cardiomyopathy Excessive catecholamine production or enhanced activity in the fetal period can lead to cardiomyocyte arrangement disorders as well as as asymmetric hypertrophy of the interventricular septum; 3, low calcium ion concentration, myofilament tension increases, myofibrillar contraction ability is enhanced, which can induce myocardial hypertrophy, but the specific etiology is not very clear.