Coughing heavily while sleeping may be cough variant asthma, gastroesophageal reflux disease, cardiac insufficiency or other causes of coughing, may require inhalation of glucocorticosteroid drugs such as budesonide aerosol, the use of pantoprazole and other acid suppression, the use of furosemide and other drugs to improve cardiac function, as well as other related treatments. 1. Cough variant asthma: the disease may require inhalation of glucocorticoid drugs such as budesonide aerosol, or even inhalation of compound preparations such as budesonide formoterol. 2. Gastroesophageal reflux disease (GERD): this disease needs to be treated with acid suppressants, such as pantoprazole and rabeprazole. 3. Cardiac insufficiency: if this is the case, it may need to be treated with regular rest and relaxation, as well as diuretics such as furosemide, and cardiac function improvement with trichothecene propylene glycol. 4. other diseases: for example, allergic rhinitis can cause night cough obvious, this time you can take montelukast sodium and other leukotriene receptor antagonists, or take cetirizine hydrochloride and other antihistamines. In summary, sleeping cough, need to clarify the cause of the disease, targeted treatment.