Jaundice and systemic metastasis in advanced stage of liver cancer cannot be used as the basis for judging the survival time of patients, and it can only be said that the survival rate of most patients with advanced stage of liver cancer is only about 10% in a year. Jaundice and systemic metastasis are more common in advanced stage of liver cancer, which indicates that the cancer cells have already metastasized and spread all over the body, and the condition is relatively serious. However, there is no way to judge the survival time of the patients based on these symptoms and manifestations, and it can only be said that most of the patients with advanced stage of liver cancer in the clinic only have a one-year survival rate of about 10%, and the prognosis is not very good. Liver cancer patients with jaundice symptoms need to actively take anti-cancer and standardized treatment. In addition to basic systemic and local radiotherapy, chemotherapy and targeted therapy, intravenous input of drugs such as compound glycyrrhizin injection is also needed to protect liver and reduce liver damage. One cannot give up treatment in advanced stage of liver cancer, and one should follow the doctor’s instruction in order to improve the quality and prolong the survival time.