There are all kinds of accidents that can happen to you without warning, such as major traffic accidents or falling from a high building. The skull defects are caused by various reasons. As the brain tissue loses the normal shielding effect of the skull, it is easy to be injured for the second time, and the skull defects can cause various symptoms and affect the appearance, which requires cranial bone repair surgery. What is the best time to perform the surgery? If the patient recovers well after the surgery, the skull repair surgery can be performed as early as possible. Our clinic advocates early cranial repair, i.e., repairing the defect when it flattens or depresses. Early cranial repair not only protects the brain from accidental injury and reduces psychological pressure, but also avoids cortical refractive movement, improves cortical blood supply, and facilitates the improvement of cerebral function, which is beneficial to the patient’s functional recovery. Early cranial bone repair not only protects the brain from accidental injury and reduces psychological pressure, but also avoids cerebral cortical refractive movement, improves cortical blood supply, and is beneficial to hyperbaric oxygen therapy. Before the operation, all patients had no contraindications to surgery, and all underwent cranial CT and frontal bone X-ray filming. The digital molding group routinely performed thin-layer CT scanning, with a layer thickness of 2mm, and 3D reconstruction of the frontal bone, and then used the “titanium mesh digital molding machine” to mold the two-dimensional titanium mesh to create a two-dimensional personalized titanium mesh restoration that was identical to the patient’s frontal bone defect, and then sterilized for spare parts; the three-dimensional easy-to-plasticize group selected three-dimensional easy-to-plasticize titanium mesh restorations that were larger than the margins of the defect by more than 2 cm, which was more than 2cm in size. The three-dimensional easy-to-mold titanium mesh that is 2cm larger than the edge of the defect is selected for the three-dimensional easy-to-mold group, and is pre-molded with traditional molds, sterilized and set aside. The most detailed preoperative preparations are made for each cranial repair patient to ensure a smooth operation. During the process, the latest repair materials are used, which have stable performance and give patients more peace of mind.