Pustules discharging a large amount of foreign material should be seen in the general surgery department and are usually sebaceous pus plugs. Antibiotic treatment as prescribed by the doctor is needed, and outpatient surgical excision if necessary. The foreign body squeezed out of the pustule, white in color, is a sebaceous gland secretion pus plug. Pus plugs are due to bacterial infection with redness, swelling, pain, and pus discharge. The pus concentrates locally to form an embolic solid, and what is squeezed out may be a white or darker colored substance that clogs the opening to form a pus plug. Milder pus plugs can be applied topically with antibiotic ointment. For example, erythromycin ointment and mupirocin ointment. If the pus plug is in a deeper location, prompt surgical debridement is needed. The deep pus will be cut and drained to remove the necrotic tissue inside. The presence of pus and the discharge of a large amount of foreign material must be consulted as soon as possible to avoid delay.