Abdominal distension and pain, leukorrhea with smell when considered for vaginitis caused by metronidazole, tinidazole and other drugs; pelvic inflammatory disease caused by ceftriaxone, metronidazole and other antibiotic treatment. 1. Vaginitis: common in trichomonas vaginitis, bacterial vaginosis, etc., can cause leukorrhea and vulvar itching and other symptoms, leukorrhea can have a peculiar smell or fishy smell, due to the pain of sexual intercourse can be caused by making the lower abdominal distension, can be clearly diagnosed through the examination of vaginal secretions, need to follow the doctor’s orders to give metronidazole, tinidazole and other medications. 2. Pelvic inflammatory disease: mainly manifested as abdominal distension and pain, increase in vaginal discharge, accompanied by odor, abdominal pain can be persistent, and aggravated after activity or sexual intercourse. The combination of history, clinical manifestations and physical signs can assist in the diagnosis. Antibiotics such as ceftriaxone and metronidazole need to be given as prescribed for anti-infective treatment. When there is abdominal distension and pain with smelly leukorrhea, it is necessary to go to the hospital in order to find out the cause and deal with it in time.