Thrombolysis can be performed for blockage of the large arteries in the brain. Thrombolysis is currently the most important treatment for cerebral infarction to restore blood flow, and has been widely proven to be effective in the treatment of cerebral infarction. It is suitable for cerebral infarction patients with neurological deficits. However, it should be noted that this treatment requires the time of onset of the disease, and only patients within 6 hours of the onset of the disease can undergo thrombolytic therapy. Contraindications to thrombolytic therapy are: (1) history of major traumatic brain injury or stroke within the past 3 months; (2) history of gastrointestinal or urinary bleeding within 3 weeks; (3) major surgery or severe trauma within 2 weeks. If thrombolytic therapy is ineffective or there are contraindications to thrombolytic therapy, arterial thrombolysis, bridging therapy and other treatments can be performed according to specific circumstances. Patients with cerebral aortic occlusion should seek timely medical treatment and choose the appropriate treatment plan under the guidance of a neurologist.