If a right-sided cerebral infarction occurs, which manifests as left-sided facial palsy and left-sided limb palsy, the corners of the mouth must be crooked to the other side. In addition, brainstem can also cause crooked corners of the mouth. Crooked corners of the mouth are not the same as the crookedness caused by facial palsy, but there is no cut-off difference in treatment. In addition to the treatment of brainstem, the appearance of crooked corners of the mouth should be treated with Chinese medicine methods, such as acupuncture and electrocautery, to help recovery. Because the crooked corners of the mouth usually have facial palsy, the face is a big problem, but it cannot be said that the symptoms cannot be recovered, and many patients can recover through treatment. Some people are left with a little after-effect, which is obvious when they laugh or speak, but it is important to treat the disease early and leave no after-effects as much as possible.