Delayed and stunted physical development is characteristic of endemic cretinism. The patient is short and disproportionate, with the lower part of the body shorter than the upper part, and has delayed skeletal development, as evidenced by the delayed appearance of the nucleus pulposus and small development. Endemic cretinism mental retardation (mentalretardation) is a syndrome that is a specialized term for mental illness. It begins before the age of 18, with an IQ below 70 and varying degrees of social adjustment difficulties. The psychiatric symptoms of Dickey’s disease actually belong to mental retardation, generally IQ less than 50 is cretinism, while 50~69 is subclinical cretinism. Intellectual backwardness is the main feature of Dickey’s disease, the severe cases are idiots, can not take care of their own lives; mild cases can work, but can not engage in skilled labor; subclinical cretinism (subcretinism) are difficult to graduate from elementary school. The mental retardation of mucocele type cretinism is a little lighter than that of neurological type, showing slow thinking and slightly higher IQ than neurological type, but as far as mental retardation is concerned, there is no essential difference between the two types of cretinism. Bone nuclei appear late, development of small patients diet therapy: 1, eat more iodine-containing food, such as kelp, nori, hairy vegetables, jellyfish, sea cucumbers, mossy vegetables, persimmons. 2, supplemental iodized salt: the domestic usually use every 2~10 kg of salt with 1 gram of potassium iodide, in order to prevent and control goiter, so that the incidence of hypothyroidism is significantly reduced. This kind of iodized salt is extremely suitable for the endemic area of endemic goiter. Women in their childbearing years should pay more attention to supplementing iodized salt to prevent their offspring from suffering from cretinism due to maternal iodine deficiency. However, some patients with hypothyroidism are caused by excessive iodine intake, which should not be treated indiscriminately and must be treated with evidence. Supplemental iodized salt, in addition to intake from iodized salt, can also be taken from iodized soy sauce and iodized bread, as well as iodine-rich kelp and nori. Avoid foods such as cabbage, bok choy, greens, cassava and walnuts, which can cause goiter.