Whether gallbladder adenomyosis requires surgery depends on the patient’s own condition and the severity of the disease. If the disease is severe and there are obvious symptoms such as persistent pain in the right upper abdomen and dyspepsia, surgery can be given. Adenomyosis of the gallbladder is a benign lesion of the gallbladder with unexplained abnormal proliferation of the mucosal epithelium and muscular layer. If the diagnosis is clear and it does not cause symptoms such as abdominal pain, bloating, dyspepsia, poor gallbladder emptying, etc., surgical treatment is not required. In general, it is important to maintain a good diet and to eat a light diet. If the diagnosis of adenomyosis of the gallbladder is confirmed, and there are obvious symptoms such as persistent pain in the right upper abdomen, poor emptying of the gallbladder, etc., and combined with gallbladder stones or other lesions, then surgery should be given after completing the relevant examinations. Currently, adenomyosis of the gallbladder is considered to have a certain risk of cancer, and it is recommended that aggressive surgical treatment is the mainstay. The same disease, the patient’s physical condition is different, different stages of the disease, the treatment method is different, should be standardized treatment under the guidance of the doctor.