Intrapulmonary metastasis of lung adenocarcinoma belongs to middle and advanced stage, for those who can tolerate surgery, they can undergo surgical treatment with chemotherapy or radiotherapy; those who cannot undergo surgery can undergo chemotherapy and radiotherapy. For those who cannot undergo surgery, chemotherapy and radiotherapy can be carried out. Patients with advanced stage can consider molecular targeted therapy. 1. Surgery: For middle and late stage lung cancer patients who can tolerate surgery, they should undergo surgery in time, and the common surgical methods are lobectomy and systematic mediastinal lymph node dissection. 2. Radiotherapy/chemotherapy: For patients with middle or late stage who have undergone surgical resection, they should also cooperate with preoperative chemotherapy or chemotherapy to reduce the tumor volume. For patients who cannot undergo surgery, radiotherapy and chemotherapy are the main measures to control tumor growth. 3. Molecular targeted therapy: if lung adenocarcinoma with intrapulmonary metastasis develops to the advanced stage, genetic testing can be carried out, and molecular targeted therapy can be carried out if molecular targets exist. Patients are advised to keep a good mindset and choose appropriate ways to treat under the guidance of doctors.