Glutamyltransferase clinically known as γ-glutamyltransferase, increased indicates liver cell damage, may be non-disease factors, disease factors (liver disease, pancreatic disease, biliary tract obstructive disease, etc.). 1. Non-disease factors: such as frequent late nights, alcohol consumption or strenuous exercise lead to high gamma-glutamyltransferase. 2. Disease factors: (1) Liver disease: for example, acute and chronic viral hepatitis, fatty liver, alcoholic hepatitis, etc. (2) Pancreatic diseases: such as pancreatitis, pancreatic tumor, etc., which can lead to high γ-glutamyl transferase. (3) Biliary tract obstructive diseases: for example, sclerosing cholangitis, primary biliary cirrhosis leading to intrahepatic obstruction caused by biliary sludge, which can cause high γ-glutamyl transferase. It is recommended to consult a doctor in time to identify the cause of the disease and follow the doctor’s instructions. Do not take medication on your own to avoid delaying your condition.