Children with fever and hot hands and feet need to carry out physical cooling, oral ibuprofen, as appropriate, to reduce fever, and need to clarify the causes of fever, according to the cause of the cause of the targeted treatment, such as urinary tract infections require the use of cefaclor and other anti-infective treatment. In pediatrics in a variety of diseases can appear fever symptoms, body temperature rise at the same time there can be “hot hands and feet” phenomenon, at this time should be warm water wipes, warm baths or the use of antipyretic patches and other ways of physical cooling, can increase the dissipation of heat, part of the children’s body temperature can be gradually reduced to normal. At the same time, we need to dynamically monitor the body temperature, for the temperature continues to rise, more than 38.5 ℃ need to use antipyretics (such as ibuprofen, acetaminophen) under the guidance of a physician to symptomatic antipyretic, and closely observe the mental condition. And need to identify the cause of the cause of treatment, such as children’s urinary tract infections, may appear in the above symptoms, with or without frequent urination, painful urination and other symptoms, need to use cefaclor and other antibacterial drugs for anti-infective treatment. All of the above drugs should be used under the guidance of a physician, and it is recommended to actively seek medical advice from a specialist physician for reasonable intervention.