Tibial bone marrow edema may subside slowly over time, but it may also result in chronic pain, pathologic fracture, necrosis of the limb, and disruption of joint function, which are related to the etiology of the cause of tibial bone marrow edema. 1. Fading: trauma is a common cause of tibial bone marrow edema, which usually fades after a long period of time and leaves no after-effects. 2. Chronic pain: The most direct consequence of tibial bone marrow edema over time is chronic pain. This may be due to increased pressure in the bone, which directly stimulates the neurovascular structures in the bone marrow, or it may be due to inflammation caused by trauma to the tibia bone, which leads to pain symptoms. 3. Pathological fracture: If bone marrow edema is caused by bone marrow infection in the tibia, it will turn into chronic osteomyelitis over time, and the bone will be destroyed, with the risk of pathological fracture. 4. Limb necrosis: If the abscess cavity of tibial bone marrow edema caused by infection increases, it will compress the surrounding tissues, leading to limb ischemia and necrosis. 5. Destruction of joint function: If tibial bone marrow edema is caused by osteoarthritis or rheumatoid arthritis, it will lead to destruction of the joint and loss of function over time. If the examination finds that there is tibial bone marrow edema, it is necessary to clarify the cause under the guidance of the doctor and carry out targeted treatment to avoid causing serious complications.