Rhinitis with a spray medicine is always nosebleed, mainly considered with improper care, adverse drug reactions. 1. Improper care: after the spray, the habitual use of cotton swabs and other supplies to clean the nasal cavity, or scratching the nose due to drug stimulation, can lead to the symptoms of nosebleeds. 2. Adverse reactions: after the application of nasal glucocorticoid drugs such as budesonide and mometasone furoate, nosebleeds and other adverse reactions may occur. 3. Other factors: the symptoms of nosebleed may also be related to external injury, nasal septal disease, nasal tumor and other diseases. In addition, other systemic diseases such as leukemia and hypertension may also cause nosebleed. Symptoms of nosebleed after the use of medication, the causes are complex. It is recommended that patients seek timely medical examination to confirm the cause of the disease and follow medical advice for disposal.