Pediatric paroxysmal cough after sleep should be treated differently according to the cause, such as upper airway cough syndrome, need to use antihistamines such as loratadine treatment; such as cough variant asthma, can use asthma medication such as glucocorticoids and other treatments. 1. Upper Airway Cough Syndrome: For example, because of children’s rhinitis and other causes of excessive nasal secretion, after lying down, the snot backflow into the back of the nose or throat, stimulate the mucous membrane of the throat triggered by coughing, coughing during the daytime, and no longer coughing after sleeping. Antihistamine drugs, such as loratadine, can be used under the guidance of a doctor. 2. Cough variant asthma: one of the most common causes of chronic cough in children, usually coughing more at night after falling asleep, coughing less during the day, sputum is very little. Can be used under the guidance of a doctor to calm the asthma drugs, such as glucocorticoids and so on. All of the above drugs need to be used under the guidance of a doctor, avoid self-medication. In addition, pediatric paroxysmal cough after sleep may also be related to other causes, it is recommended to go to the hospital in a timely manner for relevant examinations, to clarify the cause of the symptomatic treatment, follow the doctor’s instructions.