There is no clear data on the maximum number of hours to hold urine. The longer you hold urine, the more damage it will cause to your body, so it’s best not to hold urine. 1. When the bladder reaches its initial sensory capacity, that is, the first time you feel the urge to urinate, you need to urinate. If you continue to hold your urine for more than two hours, it will lead to an increase in the internal pressure of the bladder, and the urine in the bladder will return to the ureter and back to the kidneys, triggering harm. 2. Urine stays in the body for a growing period of time, easily triggering the growth of bacteria and triggering urinary tract infections. The pressure on the kidneys is great, and the kidneys will be damaged in the long run, triggering renal dysfunction. 3. Repeated overfilling of the bladder by holding urine may impair the function of the forced urethral muscle, leading to the formation of trabeculae and even diverticula, affecting the function of the bladder. Urinate as soon as possible when you feel like urinating, do a good job of daily care, drink more water, urinate more and pay attention to personal hygiene.