Usually, constipation for more than ten years has been using Kefir is not okay. Keserol is a drug for the treatment of constipation, the main role of this drug is to play the effect of lubrication, but also can stimulate the rectal intestinal wall, play the effect of softening stools, so that the stools are quickly discharged. However, the frequent use of Kerosene, rectal stimulation will increase the number of times, sensitivity will decrease, and the body once adapted to the drug, there will no longer be a significant reaction. Moreover, Keserol can cause dryness of the intestinal wall when used frequently, and the glycerin in Keserol is highly absorbent, which can easily cause habitual constipation, and dependence can also occur. There are no adverse reactions to the external use of this drug, and the contraindications are not yet clear. In addition, it is recommended that patients use Kefir under the guidance of a doctor to avoid unnecessary trouble.