Neonatal hepatitis is usually curable. Neonatal hepatitis is characterized by jaundice, elevated aminotransferases, hepatosplenomegaly, and slow onset, accompanied by loss of appetite, nausea, and vomiting. Neonatal hepatitis is mostly caused by viral infections, such as cytomegalovirus, EBV, rubella virus, cholestasis and biliary obstruction, and metabolic diseases. Neonatal hepatitis can usually be cured through aggressive treatment such as correcting the cause and liver protection. However, hepatitis caused by some diseases, such as congenital malformations caused by intrauterine infections, and metabolic diseases are difficult to cure. After the diagnosis of neonatal hepatitis is confirmed, the cause of neonatal hepatitis should be further clarified, and antiviral treatment should be given according to the cause. At the same time, actively give liver protection drugs to reduce yellow, such as compound glycyrrhizin, butanedisulfonic acid adenosylmethionine and other drugs, under the guidance of specialists, according to the changes in liver function timely adjustment of the medication, so that liver function gradually improve. Neonatal hepatitis need to consult the regular hospital in time, do not delay, so as not to cause adverse consequences.