Clinical manifestations of acute pyelonephritis include systemic symptoms such as chills and high fever, urinary symptoms such as urinary frequency, urgency, urinary pain and lumbago. 1. Systemic symptoms: fever, chills, headache, generalized pain, nausea, vomiting, etc. The body temperature is more than 38.0℃, mostly flaccid fever, but also can be arrested fever or intermittent fever. Some patients develop gram-negative bacillus bacteremia. 2. Urinary symptoms: If lower urinary tract infection occurs, there will be bladder irritation signs such as urinary urgency, urinary frequency, urinary pain and hematuria, urethral burning sensation and so on. 3. Lower back pain: the degree of lower back pain varies, mostly dull pain or soreness. At the same time can be found in the costal ridge angle or ureteral point pressure pain and (or) renal area percussion pain. Acute pyelonephritis patients are recommended to regular hospitals, standardized treatment under the guidance of physicians.