The transformation of chalazion to granuloma is not almost done, but because of secondary infection, suggesting that the condition has worsened and needs to be treated as soon as possible. Chalazion is a kind of chronic inflammatory granuloma of the blepharoplasty, small chalazion, usually can be left untreated, through the warm compresses, etc. can be self-healing, but larger need to be treated, usually choose glucocorticosteroids such as dexamethasone or incision and scraping, if not treated, it may be secondary infection, which will evolve into granuloma. Wheat grains, on the other hand, are an infectious condition. It will appear as a red lump in front of the eye, causing pain, congestion, and swelling. The presence of an emphysema can be treated with antibiotics such as levofloxacin drops to promote inflammation, ibuprofen to relieve eye pain, and surgical drainage of the pus to accelerate healing or ultrashort wave physical therapy to remove it. If it is not treated in time, it may cause a serious abscess, which can then spread to the skull and become more serious, so it needs to be treated as soon as it appears.