In addition to staying up late, some endocrine diseases, chronic toxic diseases, eye diseases, etc. can cause dark circles under the eyes. Therefore, there can be not stay up all night also have dark circles under the eyes. 1. Endocrine diseases: for example, adrenocortical insufficiency syndrome, in addition to dark circles under the eyes, this disease can also be manifested as a generalized deepening of skin pigmentation, hair loss, low blood pressure and other symptoms. 2. Chronic toxicity disease: long-term exposure to toxic environment (such as the environment containing copper, chromium, rays) can cause chronic poisoning, anemia, cyanosis and other symptoms, resulting in facial blackness, manifested as dark circles under the eyes. 3. Eye diseases: some eye inflammation (such as blepharitis) can lead to eyelid swelling, venous stasis, and then manifested as dark circles. If you don’t stay up all night and have dark circles under your eyes, and have the other symptoms mentioned above, it is recommended that you go to the hospital in time to find out the specific cause of the disease.