Sudden colic in the small stomach in the middle of the night, the causes include the following: 1. It may be due to spasmodic pain in the gastrointestinal tract caused by unclean diet or cold, there will be paroxysmal-like colic, even accompanied by nausea, vomiting, sometimes complicated by dilute watery stools. 2. It may be a sudden onset of urinary stones in the patient, including ureteral as well as bladder stones, due to the stimulation of stones leading to ureteral spasm, there will be renal colic, pain radiating pain toward the perineum or small abdomen, sometimes accompanied by significant urinary frequency, urinary urgency and hematuria. In this case, we should try to go to the hospital to find out the exact cause of the disease, and carry out systematic and standardized symptomatic treatment according to the cause. It is also important to note that when sudden stomach cramps occur at night, do not blindly take oral pain medication, which can easily cover up the condition and lead to worsening of the condition.