The difference between diclofenac sodium extended-release tablets and enteric-coated tablets is mainly reflected in the drug dosage form, duration of efficacy and the site of action of the drug, etc., the specific use of medication need to follow the doctor’s instructions. 1. Drug dosage form: extended-release tablets are long-acting preparations that are released slowly in the body, making it easier to achieve steady-state blood concentrations. Enteric-coated tablets will not disintegrate in the acidic environment of gastric fluid, and will only disintegrate and exert pharmacological effects when they reach the alkaline environment of intestinal fluid. 2. Time of action: extended-release tablets use a special process, which can make it release slowly and evenly, with a long duration of efficacy; enteric-coated tablets can’t control the speed of drug release, and the duration of efficacy is shorter than that of the former. 3. Action site: slow-release tablets can be slowly released after taking; enteric-coated tablets will be broken down and absorbed only after entering the intestine, which to a certain extent reduces the stimulation of the drug on the gastric mucous membrane, and reduces the occurrence of adverse reactions such as nausea and vomiting. Diclofenac sodium extended-release tablets and enteric-coated tablets are non-steroidal anti-inflammatory drugs with the composition of diclofenac sodium, with anti-inflammatory, analgesic and antipyretic effects. They are suitable for relieving the symptoms of joint swelling and pain of various chronic arthritis such as rheumatoid arthritis; various soft tissue rheumatic pain, such as shoulder pain; acute mild and moderate pain, and so on. Adverse drug reactions mainly include nausea, vomiting, peptic ulcer and bleeding. It is contraindicated in those who are allergic to the product, those with active peptic ulcer bleeding, and those with severe heart failure. Avoid combining with other NSAIDs, including selective COX-2 inhibitors. The use of specific drugs should be under the supervision of a physician, do not unauthorized use of drugs.