The hard skin on the soles of the feet is considered to be callus, corns, metatarsal warts, etc. The main treatments are medication, physical therapy, surgical treatment, etc., according to the specific causes of the selection of the appropriate treatment method. 1. callus: callus is long-term friction and pressure caused by the thickening of the stratum corneum, generally do not need special treatment, reduce friction after the symptoms will be alleviated, if the stratum corneum is too thick, you can use salicylic acid cream, or urea cream and vinblastine ointment for treatment. 2. Chicken eye: Chicken eye is the foot long-term friction and pressure caused by cuticle hyperplasia, you can paste the chicken eye cream, salicylic acid ointment treatment, but also through the liquid nitrogen freezing, laser treatment, for the larger chicken eye, you can also carry out the chicken eye digging out surgery. 3. metatarsal warts: is the human papilloma virus infection foot metatarsal caused by the proliferation, in the beginning will also have the symptoms of hard skin, you can use imiquimod ointment, fluorouracil ointment coated, but also through the laser, freezing and other physical methods of treatment. Scleroderma on the soles of the feet, should go to the hospital in time, clear cause of the symptomatic treatment, if you need to use drugs, should be used under the guidance of the doctor.