Post-surgical scar hyperplasia pain can be treated with both medication and surgery. 1. For early post-surgical scars, scar hyperplasia is not obvious, no local redness and swelling, you can choose the local injection of drugs, fluorouracil, tretinoin injection into the scar around the scar and within the scar tissue, so as to inhibit scar hyperplasia, thus reducing the pain symptoms. 2. For the long time after the operation, there is still pain at the scar, or the scar tissue is big and the local foreign body reaction is strong, the scar tissue can be excised under local anesthesia, and then suture the incision without tension, and then give the local injection of tretinoin after the operation to inhibit inflammatory reaction. Avoiding spicy and stimulating food after surgery, and avoiding movement and friction at the incision can prevent scar proliferation, thus reducing the occurrence of pain at the scar after surgery. Drug injections should be avoided as much as possible into the normal tissues around the scars. Medications should be applied under the guidance of a doctor.