After anal fistula surgery at home to change the medicine, first pay attention to the wound cleaning, disinfection. 1. Clean the wound: it is recommended to use warm water or 1:5000 potassium permanganate solution for sitz bath to clean the wound and promote local blood circulation. 2. Thorough disinfection: first of all, you need to use iodine povidone to disinfect, when disinfecting, pay attention to gently wipe from the inside out, pay attention to the necrotic tissue around the wound should be removed in a timely manner, it is recommended to change the medication after the bowel movement. Since the anal area can not be touched by the patient himself, it is best to change the medicine by family members. Changing the medicine can accelerate the healing of the surgical wound, but must pay attention to thoroughly remove the necrotic tissues, and keep the local dry and clean. If you are able to change the dressing at home, it is recommended that you go to the hospital outpatient clinic regularly for review, and if there is any abnormality, deal with it in time. After surgery, specific steps to change the medicine, it is recommended that you can consult the regular hospital anorectal doctor, change the medicine at home, the trauma must be recovered to a certain extent, before you can change the medicine at home, otherwise the change of medicine is not in place, easy to cause traumatic infections, pseudo healing and other complications. Therefore, if you want to change the medicine at home, firstly, according to whether the condition is allowed or not, listen to the advice of the attending doctor.