What effect will alcohol have on the human body? Drinking high concentrations of alcohol will certainly cause burns on the esophagus and gastric mucosa, causing acute gastric mucosal lesions leading to gastric bleeding, which will mainly affect the human brain and cerebellum, and the lighter ones will usually show symptoms such as coma, blindness and motor disorders, while the heavier ones can show symptoms of respiratory distress, hypothermia and even death. Drinking alcohol is actually the same as the alcoholism often seen in clinical intoxicated people, and can also damage the liver, the stomach itself with underlying diseases can also cause recurrence of gastric disease; alcohol, especially for long-term alcoholics can also cause memory effects.