An enlarged heart with normal blood pressure may be due to other organic heart diseases, such as rheumatic heart disease and dilated cardiomyopathy. Enlargement of the heart indicates that there is an abnormality in the structure of the heart. Long-term elevation of blood pressure will lead to increased load on the left heart, which in turn will lead to hypertensive heart disease, with the manifestation of enlarged left ventricle. However, elevation of blood pressure is not the only reason for enlarged heart, as many organic heart diseases also lead to enlarged heart. Rheumatic heart disease patients mainly manifested as valve stenosis or closure insufficiency, due to ventricular or atrial load, can cause heart enlargement, such as aortic valve stenosis patients will appear in the left ventricle enlarged performance, mitral valve stenosis patients may appear in the left atrium enlarged performance, so even if this kind of patients do not have high blood pressure, there will be heart enlargement. In addition, patients with dilated cardiomyopathy may also have an enlarged heart, which may be related to heredity, long-term alcohol consumption, and autoimmune diseases such as leukemia, and such patients may have an enlarged heart even if they have normal blood pressure. When heart enlargement occurs, patients need to consult a doctor in time to identify the cause of the disease and target treatment.